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Ontario Industry Updates

Notch Therapeutics Closes $85 Million Series A Financing

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Notch Therapeutics Inc., a biotechnology company developing renewable, induced pluripotent stem cell (iPSC)-derived cell therapies for cancer, announced the closing of an oversubscribed U.S. $85 million Series A financing. Proceeds from the financing will support the continuing development of Notch’s portfolio of iPSC-derived T cell therapeutic product candidates and clinical readiness of the company’s proprietary Engineered Thymic Niche (ETN) platform.

Microbix Introduces Viral Transport Medium

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Microbix Biosystems Inc., a life sciences innovator and exporter, announced the commercial availability of its viral transport medium (VTM) to support Canadian RT-PCR (molecular) testing for the virus causing COVID-19 disease. Microbix has created a secure and locally-based supply of high-quality VTM and has begun VTM production at 50,000 vials per week using semi-automated methods and is targeting more-automated production of over 400,000 vials per week by the end of its fiscal 2021.

Richardson Wealth and Bloom Burton & Co. Announce Strategic Alliance to Expand Wealth Solutions in Healthcare Sector

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Richardson Wealth Limited and Bloom Burton & Co. Inc., two of Canada’s premier independent financial services firms, have entered into a strategic alliance dedicated exclusively on the healthcare sector. This strategic alliance helps unlock growth potential for both firms.

OIRM Kick-start Innovation Investment Program

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OBIO is proud to partner with the Ontario Institute for Regenerative Medicine (OIRM), the Centre for Commercialization of Cancer Immunotherapy and Regenerative Medicine (C3i), BioInnovation Fund, Bloom Burton & Co., and Versant Ventures to ensure made-in-Ontario technologies get the strategic support they need to succeed.

Kick-Start will support successful applicants with resources to create an incorporated business, along with market assessments and an IP/commercialization plan. Investment funding of up to $100,000 and expert guidance from partners will help researcher attract early-stage investment and build value for the new company. The program will also link applicants with investors and other private sector expertise needed to attract funding and to develop and market the proposed technology.

The Globe and Mail highlights RBC's investment in new Lumira venture fund

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The Globe and Mail recently profiled Royal Bank of Canada's undisclosed investment in the country’s largest life sciences venture capital fund in two decades. Lumira is raising its fourth fund with a target of reaching US$200-million to back Canadian and U.S. drug and medical technology developers.

Satellos Receives $1 Million Investment from Parent Project Muscular Dystrophy

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Parent Project Muscular Dystrophy (PPMD), a nonprofit organization leading the fight to end Duchenne muscular dystrophy (Duchenne), announced a $1 million programmatic investment in Satellos Bioscience to support the development of a new regenerative medicine for the therapeutic treatment of Duchenne.

Vasomune Therapeutics Announces Initiation of the First-in-Human Clinical Trial of a Potential Vascular Normalization COVID-19 Treatment

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Vasomune, Inc., a clinical-stage biopharmaceutical company, announced the first subjects have been dosed in a Phase 1 study of AV-001 in healthy subjects. AV-001 is a first-in-class therapeutic that targets the Tie2 tyrosine kinase receptor, a key regulatory protein in the vasculature responsible for maintaining normal vascular function. Should the benefit demonstrated in animal studies translate to the clinic, AV-001 has the potential to improve survival and shorten the duration of hospitalization for patients hospitalized with COVID-19.

Microbix and Copan Italia Execute Strategic Agreement

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Microbix Biosystems Inc., a life sciences innovator and exporter, and Copan Italia S.p.A., the global leader in specimen collection technologies, announced their execution of a strategic agreement in relation to Microbix’s quality assessment products (QAPs™) and Copan’s flocked devices (FLOQ®). Twelve such FLOQ-based QAPs SKUs have already been created and introduced. Of those, fully IVD-regulated REDxFLOQ controls are now available to support lab-based molecular-test workflows for the SARS-CoV-2 virus (the cause of COVID-19 disease).

MCI Onehealth Closes $30 Million Initial Public Offering

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MCI Onehealth, a Toronto-based healthtech company, has closed $30 million CAD for its initial public offering (IPO). The company is working on several software products, including an artificial intelligence-enabled technology aimed to increase the rate of detection for chronic disease and improve overall clinical standards.

ManagingLife's digital solution helps manage chronic pain disability claims

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ManagingLife, a private developer of the digital pain management solution, Manage My Pain, announced the publication of its first case study of its solution being used by clients with disability. The case study highlights Manage My Pain's impact on clients receiving disability benefits from RBC Insurance in terms of their claims experience and claim durations.

Ripple Therapeutics secures Licensing Agreement and Series A Financing led by Théa Open Innovation

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Ripple Therapeutics Corporation, a clinical stage, ophthalmology-focused developer of novel therapeutics, announced the signing of an exclusive Licensing Agreement for the rights to their lead product, IBE-814, for North America and Europe with Théa Open Innovation ("TOI") a wholly owned subsidiary of Laboratoires Théa, the leading independent ophthalmology pharmaceutical company in Europe. In addition to the Licensing Agreement, Ripple announced that TOI is leading their Series A Financing.